Colorful images that represent the different research areas of the lab’s work.

Development, Regeneration, and Rare Diseases of the Musculoskeletal System

The overarching aim of the Goldhamer Lab is to understand fundamental molecular and cellular mechanisms that regulate normal musculoskeletal development and how these mechanisms are co-opted in disease states. Areas of investigation include the regulation of stem cell fates in embryonic development and muscle regeneration, the molecular basis of stem cell dysfunction in impaired regeneration, and the mechanisms of stem cell reprogramming in diseases manifested by the accumulation of fat, fibrotic tissues, and heterotopic bone in skeletal muscle tissue. Mouse molecular genetics, advanced histological methods, and genomics approaches are some of the complementary tools we use to address these and related areas in developmental biology, stem cell biology, and disease pathogenesis.

Read More About Our Research Areas!

Recent News

2026 SURF Award Recipients

Congrats to Kate Foley and Elizabeth Evans, who have been selected to receive 2026 Summer Undergraduate Research Fund awards for their proposed projects! We are very excited for them and delighted that they will be joining us this summer!

Dr. David Goldhamer Inducted into the Connecticut Academy of Science and Engineering

Congratulations to our own Dr. Goldhamer, who was elected to the Connecticut Academy of Science and Engineering (CASE). He is recognized for achieving scientific distinction through original contributions to science and engineering! See UConn Today - Making CASE: Nine UConn Faculty Inducted into Prestigious Group

Fascial Slit Paper!

Congrats to Russ on his first author publication, and everyone else involved! Check it out here:
Hanson, L. R., Scalise, K. L., Esch, R. M., Nevo, L., and Goldhamer, D. J. (2026). The role of muscle fascia in heterotopic ossification and maintenance of skeletal muscle integrity in fibrodysplasia ossificans progressiva. Bone 207, https://doi.org/10.1016/j.bone.2026.117829

Welcome Emmanuel!

We are happy to announce Emmanuel Kolawole has officially joined The Goldhamer Lab! We are excited for him to begin his journey in studying muscle regeneration!

All News!

Courses Taught By Dr. Goldhamer

MCB 3219. Developmental and Regenerative Biology

MCB 3220. Developmental Biology Laboratory

Contact Information

Phone: 860-486-8337
david.goldhamer@uconn.edu
Address: 91 North Eagleville Road

Unit 3125

Storrs, CT 06269-3125

Office: Biology/Physics Building G24